#2. Andrew Luck (2012-2019): The Colts selected Luck as the first-overall pick in the 2012 NFL Draft and he was touted to be the next Peyton Manning. Injuries kept him from reaching his full potential and eventually ended his career. In his six seasons with the Indianapolis Colts, Luck had 171 touchdowns and four Pro Bowls. He carried the Colts to the playoffs all three of his first seasons, making the 2014 AFC title game. (Photo Credit: AP)